Accelerate spatial biology: PathcoreFlow™ 4.0 eliminates bottlenecks in multiplex IF imaging workflows

  • January 22nd 2025
  • in

Working with high-plex images—generated by modern multiplex immunofluorescence (mIF) platforms for spatial biology applications—often present significant challenges. File storage and retrieval, collaboration barriers, and other platform limitations hinder robust analysis and the speed at which insights can be generated.

Recent developments in spatial biology have led to an explosion of high dimensional images. These high-plex images are extremely challenging to store, share, and analyze. They also come in multiple proprietary image formats that aren’t compatible with most software platforms. Moreover, managing the storage costs of these extensive datasets presents a considerable economic challenge.

Spatial biology and other highplex imaging applications need better software tools and scalable IT infrastructure to deal with these uniquely large datasets.

PathcoreFlow 4.0 Launch
Introducing PathcoreFlow 4.0: Easily share images and render settings, access unlimited channels and histograms, and take advantage of multi-platform and file type compatibility.

Introducing PathcoreFlow™ 4.0: Enhancing multiplex IF imaging workflows with seamless collaboration, advanced data insight tools, and innovative efficiency

With PathcoreFlow™ 4.0, we’ve reimagined the way teams collaborate, view, and analyze complex mIF and high-plex images. PathcoreFlow 4.0 is the most comprehensive viewing and collaboration solution for mIF imaging and spatial biology applications. While designed to easily support high-plex images, the latest version prioritizes a user-friendly software that supports unlimited channels, high-resolution histograms, and support for a broad range of multiplex spatial biology platforms and image analysis systems.

With GLP compliance, SSO, ISO 27001 certification, and a robust back-end, PathcoreFlow 4.0 is engineered to make digital pathology the preferred option for every member of a multi-disciplinary pathology team—researchers, pathologists, toxicological pathologists, IT leaders and support staff, business and RA/QA leaders, and more. Purpose-built to tackle industry pain points, this cutting-edge platform redefines how pathology and research teams manage their high-plex imaging workflows.

The challenges of imaging workflows

While the industry has seen many technological advances and increased global collaboration, imaging workflows still have a host of challenges. Recent advances in spatial biology have led to an explosion of datasets that are becoming too big to store, share and analyze. 

Other challenges include:

  • Team collaboration: Storing and sharing images, and managing image render settings is cumbersome, leading to inconsistencies and inefficiencies.

  • Platform compatibility: Lack of interoperability with various imaging platforms creates bottlenecks, limiting workflow options.

  • High-plex image analysis: Traditional tools struggle to support the complexity of high-plex imaging, hindering precision and insight.

  • Technology failures: Slow or unreliable image management/viewing software that struggle with large images, decreasing productivity.

  • Data storage costs: The extreme size of high-plex image files makes data storage costly or inefficient.

What makes PathcoreFlow 4.0 different?

PathcoreFlow is a connected workspace for digital pathology, helping research teams organize, retain and collaborate better by bridging your digital pathology systems together. 

PathcoreFlow 4.0 isn’t just an upgrade—it’s a reimagined digital pathology solution. Key features include:

  • Collaborate with ease: Access large files from anywhere and share with colleagues via a simple link—high-speed streaming of high-resolution images means no waiting time for downloads and uploads and images are viewable instantly. 

  • Reduce storage costs: Pathcore’s hierarchical storage management (HSM) minimizes storage and bandwidth costs by automatically moving aging data across multiple storage tiers. With HSM, local storage infrastructure or letting the budget determine whether to let go of image files will be stressors of the past.

  • Save and share render settings: Customize, save, and share image render settings to ensure consistent collaboration.

  • Unlimited channels & histograms: Analyze high-plex images with precision using high-resolution histograms and support for unlimited channels, aiding in the differentiation of true signals from background noise.

  • Multi-platform compatibility: Easily integrate with a full range of multiplex spatial biology platforms and image analysis systems, ensuring flexibility and scalability.

PathcoreFlow Multi-platform compatibility
Easily integrate with a full range of multiplex spatial biology platforms and image analysis systems, ensuring flexibility and scalability.

With these features, PathcoreFlow 4.0 sets a new standard for pre-clinical pathology imaging workflows and image management systems.

What this means

PathcoreFlow 4.0 delivers more than just cutting-edge tools—it transforms workflows:

  • Save time: Streamline imaging processes with intuitive, user-friendly features.

  • Improve efficiency: Foster seamless collaboration across teams, regardless of location.

  • Enhance accuracy: Ensure reliable data visualization and analysis, minimizing errors and maximizing insights.

Pathology and research teams can now focus on the science, while PathcoreFlow 4.0 handles the technology.

Ami Lau, COO of Glint Lab, shares how PathcoreFlow has helped their team overcome complex image analysis challenges, unlocking new possibilities in preclinical and drug discovery research.

“We rely on PathcoreFlow to deliver images, annotations, and analysis results worldwide; its seamless integration with Visiopharm is key to our image analysis as a service offering.” 

-Ami Lau, COO of Glint Lab

Reimagine your workflows

Ready to revolutionize your imaging workflows? Discover how PathcoreFlow 4.0 can elevate your approach to multiplex IF imaging and spatial biology data.

Join our upcoming webinar: 

Scalable Image Management System for Spatial Biology
February 13, 2025 @ 1pm EST | 10am PST | 6pm GMT
Register today: https://tinyurl.com/pathcoreflow4

Request a demo: https://pathcore.com/contact/sales

PathcoreFlow 4.0 is already trusted by leading teams in spatial biology and mIF imaging. Join them today and see the difference it makes.